Definitions for pyrroline carboxylate reductases
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U.S. National Library of Medicine
Pyrroline Carboxylate Reductases
A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 220.127.116.11) and the 5-oxidoreductase (EC 18.104.22.168). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.
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