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1. (n.) progeria
a rare congenital abnormality characterized by premature and rapid aging, the affected individual appearing in childhood as an aged person.
Etymology: (1900–05; < Gk progēr(ōs) prematurely old (pro-pro -2+-gēros, adj. der. of gêras old age) + -ia)
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| Definition of 'progeria' |
Princeton's WordNet |
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1. (noun) progeria
a rare abnormality marked by premature aging (grey hair and wrinkled skin and stooped posture) in a child
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| Definition of 'progeria' |
U.S. National Library of Medicine |
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1. progeria
An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.
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Definitions of progeria 
