Definitions for prochirality
prochi·ral·i·ty

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1. prochiralitynoun

   the property displayed by a prochiral molecule or other entity; protostereoisomerism

WikipediaRate this definition:0.0 / 0 votes

1. Prochirality

   In stereochemistry, prochiral molecules are those that can be converted from achiral to chiral in a single step. An achiral species which can be converted to a chiral in two steps is called proprochiral.If two identical substituents are attached to a sp3-hybridized atom, the descriptors pro-R and pro-S are used to distinguish between the two. Promoting the pro-R substituent to higher priority than the other identical substituent results in an R chirality center at the original sp3-hybridized atom, and analogously for the pro-S substituent. A trigonal planar sp2-hybridized atom can be converted to a chiral center when a substituent is added to the re or si (from Latin rectus 'right', and sinister 'left') face of the molecule. A face is labeled re if, when looking at that face, the substituents at the trigonal atom are arranged in increasing Cahn-Ingold-Prelog priority order (1 to 2 to 3) in a clockwise order, and si if the priorities increase in anti-clockwise order; note that the designation of the resulting chiral center as S or R depends on the priority of the incoming group.The concept of prochirality is necessary for understanding some aspects of enzyme stereospecificity. Alexander Ogston pointed out that when a symmetrical molecule is placed in an asymmetric environment, such as the surface of an enzyme, supposedly identically placed groups become distinguishable. In this way he showed that earlier exclusion of non-chiral citrate as a possible intermediate in the tricarboxylate cycle was mistaken.

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1. Prochirality

   In stereochemistry, prochiral molecules are those that can be converted from achiral to chiral in a single step. If two identical substituents are attached to a sp³-hybridized atom, the descriptors pro-R and pro-S are used to distinguish between the two. Promoting the pro-R substituent to higher priority than the other identical substituent results in an R chirality center at the original sp³-hybridized atom, and analogously for the Pro-S substituent. A trigonal planar sp²-hybridized atom can be converted to a chiral center when a substituent is added to the re or si face of the molecule. A face is labeled re if, when looking at that face, the substituents at the trigonal atom are arranged in decreasing Cahn-Ingold-Prelog priority order in a clockwise order, and si if the priorities decrease in counter-clockwise order; but the designation of the resulting chiral center as S or R depends on the priority of the incoming group.

How to pronounce prochirality?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say prochirality in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of prochirality in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of prochirality in Pythagorean Numerology is: 1

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Prochirality
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Prochirality
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=prochirality