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1. (n.) prion
a tiny proteinaceous particle, likened to viruses and viroids, but having no genetic component, thought to be an infectious agent in bovine spongiform encephalopathy, Creutzfeldt-Jakob disease, and similar encephalopathies.
Etymology: (1980–85; pr (oteinaceous ) +i (nfectious ) + -on1)
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1. (noun) prion
(microbiology) an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system
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Definitions of prion 
