What does phosphopantetheine mean?
Definitions for phosphopantetheine
phos·pho·pan·teth·eine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word phosphopantetheine.
Wiktionary
phosphopantetheinenoun
A derivative of coenzyme A essential to the function of carrier proteins
Wikipedia
Phosphopantetheine
Phosphopantetheine, also known as 4'-phosphopantetheine, is a prosthetic group of several acyl carrier proteins including the acyl carrier proteins (ACP) of fatty acid synthases, ACPs of polyketide synthases, the peptidyl carrier proteins (PCP), as well as aryl carrier proteins (ArCP) of nonribosomal peptide synthetases (NRPS). It is also present in formyltetrahydrofolate dehydrogenase.Subsequent to the expression of the apo acyl carrier protein, 4'-phosphopantetheine moiety is attached to a serine residue. The coupling involves formation of a phosphodiester linkage. This coupling is mediated by acyl carrier protein synthase (ACPS), a 4'-phosphopantetheinyl transferase. Phosphopantetheine prosthetic group covalently links to the acyl group via a high energy thioester bond. The flexibility and length of the phosphopantetheine chain (approximately 2 nm) allows the covalently tethered intermediates to access spatially distinct enzyme-active sites. This accessibility increases the effective molarity of the intermediate and allows an assembly line-like process.
Wikidata
Phosphopantetheine
4'-Phosphopantetheine is an essential prosthetic group of acyl carrier protein and peptidyl carrier proteins and aryl carrier proteins derived from Coenzyme A. It is also present in formyltetrahydrofolate dehydrogenase.
Numerology
Chaldean Numerology
The numerical value of phosphopantetheine in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of phosphopantetheine in Pythagorean Numerology is: 7
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"phosphopantetheine." Definitions.net. STANDS4 LLC, 2024. Web. 23 Apr. 2024. <https://www.definitions.net/definition/phosphopantetheine>.
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