Definitions for pemphigus, benign familial
This page provides all possible meanings and translations of the word pemphigus, benign familial
U.S. National Library of Medicine
Pemphigus, Benign Familial
An autosomal dominantly inherited skin disorder characterized by recurrent eruptions of vesicles and BULLAE mainly on the neck, axillae, and groin. Mutations in the ATP2C1 gene (encoding the secretory pathway Ca2++/Mn2++ ATPase 1 (SPCA1)) cause this disease. It is clinically and histologically similar to DARIER DISEASE - both have abnormal, unstable DESMOSOMES between KERATINOCYTES and defective CALCIUM-TRANSPORTING ATPASES. It is unrelated to PEMPHIGUS VULGARIS though it closely resembles that disease.
Find a translation for the pemphigus, benign familial definition in other languages:
Select another language:
Discuss these pemphigus, benign familial definitions with the community:
Use the citation below to add this definition to your bibliography:
"pemphigus, benign familial." Definitions.net. STANDS4 LLC, 2014. Web. 29 Jul 2014. <http://www.definitions.net/definition/pemphigus, benign familial>.