Definitions for pathogenesisˌpæθ əˈdʒɛn ə sɪs; pəˈθɒdʒ ə ni
This page provides all possible meanings and translations of the word pathogenesis
the origination and development of a disease
The origin and development of a disease.
The mechanism whereby something causes a disease.
The pathogenesis of a disease is the mechanism that causes the disease. The term can also describe the origin and development of the disease, and whether it is acute, chronic, or recurrent. The word comes from the Greek pathos and genesis. Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown. Most diseases are caused by multiple processes. For example, certain cancers arise from dysfunction of the immune system. Often, a potential etiology is identified by epidemiological observations before a pathological link can be drawn between the cause and the disease.
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As a major natural antioxidant in the body, uric acid has been estimated to account for more than 50 percent of the antioxidant capacity of plasma, with these potentially neuro-protective properties, uric acid has been hypothesized to protect against oxidative stress, a prominent contributor to dopaminergic neuron degeneration in Parkinson's disease, which may also play an important role in the pathogenesis of Alzheimer’s disease.
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"pathogenesis." Definitions.net. STANDS4 LLC, 2016. Web. 12 Feb. 2016. <http://www.definitions.net/definition/pathogenesis>.