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 Definitions of papillon-lefevre disease  

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Definition of 'papillon-lefevre disease' U.S. National Library of Medicine 

1.  papillon-lefevre disease
Rare, autosomal recessive disorder occurring between the first and fifth years of life. It is characterized by palmoplantar keratoderma with periodontitis followed by the premature shedding of both deciduous and permanent teeth. Mutations in the gene for CATHEPSIN C have been associated with this disease.

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