Definitions of pantothenate kinase-associated neurodegeneration

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Definition of 'pantothenate kinase-associated neurodegeneration'

U.S. National Library of Medicine

1. pantothenate kinase-associated neurodegeneration
A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)

'pantothenate kinase-associated neurodegeneration' - Nearby Entries
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