Definitions for pancreatic elastase

This page provides all possible meanings and translations of the word pancreatic elastase

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  1. Pancreatic elastase

    Pancreatic elastase is a form of elastase that is formed in the pancreas. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. The first isozyme, pancreatic elastase 1 was initially thought to be expressed in the pancreas. However it was later discovered that it was the only chymotrypsin-like elastase that was not expressed in the pancreas. Hence this protein has been renamed elastase 1 or chymotrypsin-like elastase family, member 1. For a period of time, it was thought that that ELA1 / CELA1 was not transcribed into a protein. However it was later discovered that it was expressed in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.

U.S. National Library of Medicine

  1. Pancreatic Elastase

    A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.

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