Definitions for oxalobacter formigenes
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Oxalobacter formigenes is an oxalate-degrading anaerobic bacterium that colonizes the large intestine of numerous vertebrates, including humans. O. formigenes and humans share a beneficial symbiosis. Quinolone, a broad-spectrum antibiotic, kills O. formigenes. If a person's gastrointestinal tract lacks this bacterium, and therefore lacks the primary source for the Oxalyl-CoA decarboxylase enzyme, then the GI tract cannot degrade calcium oxalate. Such an imbalance may facilitate the formation of Calcium Oxalate based kidney stones.
U.S. National Library of Medicine
The sole species of the genus Oxalobacter consisting of straight or curved gram-negative rods with rounded ends. Cells are nonmotile, nonsporing, and use oxylates as the only source of CARBON and energy, with formate and CARBON DIOXIDE as end products. They are isolated from lake sediments and from the rumen or large bowel of humans and animals. (From Bergey's Manual of Determinative Bacteriology, 9th ed)
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