What does overdominance mean?
Definitions for overdominance
over·dom·i·nance
This dictionary definitions page includes all the possible meanings, example usage and translations of the word overdominance.
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Wiktionary
overdominancenoun
The state of a gene wherein a heterozygote has a higher risk of disease than either of its homozygote parents.
Wikipedia
Overdominance
Overdominance is a rare condition in genetics where the phenotype of the heterozygote lies outside the phenotypical range of both homozygous parents. Overdominance can also be described as heterozygote advantage regulated by a single genomic locus, wherein heterozygous individuals have a higher fitness than homozygous individuals. However, not all cases of the heterozygote advantage are considered overdominance, as they may be regulated by multiple genomic regions. Overdominance has been hypothesized as an underlying cause for heterosis (increased fitness of hybrid offspring).
Wikidata
Overdominance
Overdominance is a condition in genetics where the phenotype of the heterozygote lies outside the phenotypical range of both homozygote parents. Overdominance can also be described as heterozygote advantage, wherein heterozygous individuals have a higher fitness than homozygous individuals. An example in humans is sickle cell anemia. This condition is determined by a single polymorphism. Possessors of the deleterious allele have lower life expectancy, with homozygotes rarely reaching 50 years of age. However, this allele also yields some resistance to malaria. Thus in regions where malaria exerts or has exerted a strong selective pressure, sickle cell anemia has been selected for its conferred partial resistance to the disease. While homozygotes will have either no protection from malaria or a dramatic propensity to sickle cell anemia, heterozygotes enjoy a partial resistance to both.
Numerology
Chaldean Numerology
The numerical value of overdominance in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of overdominance in Pythagorean Numerology is: 3
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"overdominance." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/overdominance>.
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