Definitions for osteoclastˈɒs ti əˌklæst
This page provides all possible meanings and translations of the word osteoclast
cell that functions in the breakdown and resorption of bone tissue
A large multinuclear cell associated with the resorption of bone
An instrument for performing osteoclasis.
An osteoclast is a type of bone cell that removes bone tissue by removing its mineralized matrix and breaking up the organic bone. This process is known as bone resorption. Osteoclasts were discovered by Kolliker in 1873. Osteoclasts and osteoblasts are instrumental in controlling the amount of bone tissue: osteoblasts form bone, osteoclasts resorb bone. Osteoclasts are formed by the fusion of cells of the monocyte-macrophage cell line. Osteoclasts are characterized by high expression of tartrate resistant acid phosphatase and cathepsin K.
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