cell that functions in the breakdown and resorption of bone tissue
(Physiol.) Same as myeloplax, a large multinucleate cell within the bone, which functions in the absroption and removal of bone tissue.
Origin: [Osteo- + Gr. kla^n to break.]
A large multinuclear cell associated with the resorption of bone
An instrument for performing osteoclasis.
An osteoclast is a type of bone cell that removes bone tissue by removing its mineralized matrix and breaking up the organic bone. This process is known as bone resorption. Osteoclasts were discovered by Kolliker in 1873. Osteoclasts and osteoblasts are instrumental in controlling the amount of bone tissue: osteoblasts form bone, osteoclasts resorb bone. Osteoclasts are formed by the fusion of cells of the monocyte-macrophage cell line. Osteoclasts are characterized by high expression of tartrate resistant acid phosphatase and cathepsin K.
The numerical value of osteoclast in Chaldean Numerology is: 4
The numerical value of osteoclast in Pythagorean Numerology is: 3
Sample Sentences & Example Usage
Denosumab also decreases bone resorption by inhibiting maturation of osteoclasts through binding to a receptor on the surface of 'pre-osteoclast cells,'.
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Translations for osteoclast
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