This page provides all possible meanings and translations of the word osteocalcin
WiktionaryRate this definition:(0.00 / 0 votes)
A protein found in bone and dentin, manufactured by osteoblasts. It plays a role in mineralization and calcium ion homeostasis.
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Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein, is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene.
U.S. National Library of MedicineRate this definition:(0.00 / 0 votes)
Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.
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