Definitions for osteoblastˈɒs ti əˌblæst
This page provides all possible meanings and translations of the word osteoblast
Random House Webster's College Dictionary
os•te•o•blastˈɒs ti əˌblæst(n.)
a bone-forming cell.
Category: Cell Biology
Origin of osteoblast:
osteoblast, bone-forming cell(noun)
a cell from which bone develops
A mononucleate cell from which bone develops.
Osteoblasts are mononucleate cells that are responsible for bone formation; in essence, osteoblasts are specialized fibroblasts that in addition to fibroblastic products, express bone sialoprotein and osteocalcin. Osteoblasts produce a matrix of osteoid, which is composed mainly of Type I collagen. Osteoblasts are also responsible for mineralization of this matrix. Zinc, copper and sodium are some of the minerals required in this process. Bone is a dynamic tissue that is constantly being reshaped by osteoblasts, which are in charge of production of matrix and mineral, and osteoclasts, which break down the tissue. The number of osteoblasts tends to decrease with age, affecting the balance of formation and resorption in the bone tissue, and potentially leading to osteoporosis.
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