Definitions for oseltamivir
This page provides all possible meanings and translations of the word oseltamivir
An antiviral drug used to treat influenza; it is a derivative of shikimic acid, and is marketed as Tamiflu.
Oseltamivir INN, marketed under the trade name Tamiflu, is an antiviral drug, which may slow the spread of influenza virus between cells in the body by stopping the virus from chemically cutting ties with its host cell. The drug is taken orally in capsules or as a suspension. It is used to treat influenza A virus and influenza B virus. Oseltamivir is a prodrug, a inactive chemical, which is converted into its active form by metabolic process after it is taken into the body. It was the first orally active neuraminidase inhibitor commercially developed. It was developed by C.U. Kim, W. Lew, and X. Chen of US-based Gilead Sciences, and is marketed by Genentech. There have been questions about oseltamivir's efficacy as the company that manufactures it has refused to release the trial data for independent analysis. In light of this neuramidase inhibitors such as oseltamivir may be modestly effective in decreasing the time people are sick and prevention of influenza A and B infections in children. Together these studies suggest oseltamivir reduces the median time to symptom alleviation 0.5–1 day. It is unclear if this medication effects transmission of influenza in adults. They however can increase rates of vomiting.
U.S. National Library of Medicine
An acetamido cyclohexene that is a structural homolog of SIALIC ACID and inhibits NEURAMINIDASE.
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