Definitions for orphenadrine

This page provides all possible meanings and translations of the word orphenadrine

Princeton's WordNet

  1. orphenadrine, Norflex(noun)

    a skeletal muscle relaxant (trade name Norflex) used to treat severe muscle strain and Parkinsonism

Wiktionary

  1. orphenadrine(Noun)

    An anticholinergic drug of the ethanolamine antihistamine class, closely related to diphenhydramine, used to treat painful muscle spasm and some aspects of Parkinson's disease.

Freebase

  1. Orphenadrine

    Orphenadrine is an anticholinergic drug of the ethanolamine antihistamine class with prominent CNS and peripheral actions used to treat painful muscle spasms, other similar conditions, as well as the treatment of some aspects of Parkinson's Disease. It is closely related to diphenhydramine. Therefore, it is related to other drugs used for Parkinson's like benztropine and trihexyphenidyl, and it is also structurally related to nefopam, which is a centrally-acting yet non-opioid analgesic. The combination of anticholinergic effects and CNS penetration make orphenadrine useful for pain of all etiologies, including pain from: radiculopathy, muscle pain, and headaches. Orphenadrine has approximately 58% of the anticholinergic potency of atropine at equivalent doses. Orphenadrine is most often used against pain and muscle spasm of various etiologies including lumbago, sciatica, and injury. It is quite useful against allergic symptoms and other histamine-related effects, such as those from hay fever, other allergies, and histamine release from many opioid analgesics. Where available for prescription compounding, orphenadrine can also be prepared for topical administration and works slightly better than diphenhydramine for this purpose.

U.S. National Library of Medicine

  1. Orphenadrine

    A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

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"orphenadrine." Definitions.net. STANDS4 LLC, 2014. Web. 16 Apr. 2014. <http://www.definitions.net/definition/orphenadrine>.

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