Definitions of orphan nuclear receptors

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Definition of 'orphan nuclear receptors'

U.S. National Library of Medicine

1. orphan nuclear receptors
A broad category of receptor-like proteins that may play a role in transcriptional-regulation in the CELL NUCLEUS. Many of these proteins are similar in structure to known NUCLEAR RECEPTORS but appear to lack a functional ligand-binding domain, while in other cases the specific ligands have yet to be identified.

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