Definitions for optic nerve glioma

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  1. Optic nerve glioma

    Optic nerve glioma, a form of glioma which affects the optic nerve, is often one of the central nervous system manifestations of Neurofibromatosis 1. Optic gliomas are usually pilocytic tumors, and can involve the optic nerve or optic chiasm. Optic gliomas are usually associated with neurofibromatosis type 1.

U.S. National Library of Medicine

  1. Optic Nerve Glioma

    Glial cell derived tumors arising from the optic nerve, usually presenting in childhood. Roughly 50% are associated with NEUROFIBROMATOSIS 1. Clinical manifestations include decreased visual acuity; EXOPHTHALMOS; NYSTAGMUS, PATHOLOGIC; STRABISMUS; pallor or swelling of the optic disc; and INTRACRANIAL HYPERTENSION. The tumor may extend into the optic chiasm and hypothalamus. (Adams et al., Principles of Neurology, 6th ed, p681)

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