Definitions for operonˈɒp əˌrɒn
This page provides all possible meanings and translations of the word operon
Random House Webster's College Dictionary
a set of two or more adjacent cistrons whose transcription is under the coordinated control of a promoter, an operator, and a regulator gene.
Origin of operon:
< F opéron (1960), der. of opérer to work
a segment of DNA containing adjacent genes including structural genes and an operator gene and a regulatory gene
A unit of genetic material that functions in a coordinated manner by means of an operator, a promoter, and structural genes that are transcribed together.
In genetics, an operon is a functioning unit of genomic DNA containing a cluster of genes under the control of a single regulatory signal or promoter. The genes are transcribed together into an mRNA strand and either translated together in the cytoplasm, or undergo trans-splicing to create monocistronic mRNAs that are translated separately, i.e. several strands of mRNA that each encode a single gene product. The result of this is that the genes contained in the operon are either expressed together or not at all. Several genes must be both co-transcribed and co-regulated to define an operon. Originally, operons were thought to exist solely in prokaryotes, but since the discovery of the first operons in eukaryotes in the early 1990s, more evidence has arisen to suggest they are more common than previously assumed. In general, expression of prokaryotic operons leads to the generation of polycistronic mRNAs, while eukaryotic operons lead to monocistronic mRNAs. Operons have also been found in viruses such as bacteriophages. For example, T7 phages have two operons—the first one codes for various products including a special T7 RNA polymerase which can bind to and transcribe the second operon—which includes a lysis gene meant to cause the host cell to burst.
U.S. National Library of Medicine
In bacteria, a group of metabolically related genes, with a common promoter, whose transcription into a single polycistronic MESSENGER RNA is under the control of an OPERATOR REGION.
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