Definitions of oncolytic viruses

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Definition of 'oncolytic viruses'

U.S. National Library of Medicine

1. oncolytic viruses
Tumor-selective, replication competent VIRUSES that have antineoplastic effects. This is achieved by producing cytotoxicity-enhancing proteins and/or eliciting an antitumor immune response. They are genetically engineered so that they can replicate in CANCER cells but not in normal cells, and are used in ONCOLYTIC VIROTHERAPY.

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