Definitions for oligonucleotide probes

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  1. Oligonucleotide Probes

    Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.

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"oligonucleotide probes." Definitions.net. STANDS4 LLC, 2015. Web. 27 Mar. 2015. <http://www.definitions.net/definition/oligonucleotide probes>.

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