What does oligonucleotide mean?
Definitions for oligonucleotide
ˌɒl ɪ goʊˈnu kli əˌtaɪd, -ˈnyu-oligonu·cleotide
This dictionary definitions page includes all the possible meanings, example usage and translations of the word oligonucleotide.
Princeton's WordNet
oligonucleotide, oligonoun
(biochemistry) a polynucleotide whose molecules contain relatively few nucleotides
Wiktionary
oligonucleotidenoun
A short sequence of nucleotides (RNA or DNA), typically with twenty or fewer base pairs.
Wikipedia
Oligonucleotide
Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can be manufactured as single-stranded molecules with any user-specified sequence, and so are vital for artificial gene synthesis, polymerase chain reaction (PCR), DNA sequencing, molecular cloning and as molecular probes. In nature, oligonucleotides are usually found as small RNA molecules that function in the regulation of gene expression (e.g. microRNA), or are degradation intermediates derived from the breakdown of larger nucleic acid molecules. Oligonucleotides are characterized by the sequence of nucleotide residues that make up the entire molecule. The length of the oligonucleotide is usually denoted by "-mer" (from Greek meros, "part"). For example, an oligonucleotide of six nucleotides (nt) is a hexamer, while one of 25 nt would usually be called a "25-mer". Oligonucleotides readily bind, in a sequence-specific manner, to their respective complementary oligonucleotides, DNA, or RNA to form duplexes or, less often, hybrids of a higher order. This basic property serves as a foundation for the use of oligonucleotides as probes for detecting specific sequences of DNA or RNA. Examples of procedures that use oligonucleotides include DNA microarrays, Southern blots, ASO analysis, fluorescent in situ hybridization (FISH), PCR, and the synthesis of artificial genes. Oligonucleotides are composed of 2'-deoxyribonucleotides (oligodeoxyribonucleotides), which can be modified at the backbone or on the 2’ sugar position to achieve different pharmacological effects. These modifications give new properties to the oligonucleotides and make them a key element in antisense therapy.
ChatGPT
oligonucleotide
An oligonucleotide is a short sequence of nucleotides (RNA or DNA), typically with twenty or fewer bases. These sequences can be synthesized for use in various genetic research or testing procedures, including diagnostics, sequencing, and gene synthesis. They are usually found in a laboratory setting and are crucial tools in genetic and forensic research.
Wikidata
Oligonucleotide
Oligonucleotides are short, single-stranded DNA or RNA molecules that have a wide range of applications in genetic testing, research, and forensics. Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can be manufactured with any user-specified sequence, and so are vital for artificial gene synthesis, polymerase chain reaction, DNA sequencing, library construction and as molecular probes. In nature, oligonucleotides are usually found as small RNA molecules that function in the regulation of gene expression, or are degradation intermediates derived from the breakdown of larger nucleic acid molecules. Oligonucleotides are characterized by the sequence of nucleotide residues that comprise the entire molecule. The length of the oligonucleotide is usually denoted by "-mer". For example, an oligonucleotide of six nucleotides is an hexamer, while one of 25 nt would usually be called a "25-mer". Oligonucleotides readily bind, in a sequence-specific manner, to their respective complementary oligonucleotides, DNA, or RNA to form duplexes or, less often, hybrids of a higher order. This basic property serves as a foundation for the use of oligonucleotides as probes for detecting DNA or RNA. Examples of procedures that use oligonucleotides include DNA microarrays, Southern blots, ASO analysis, fluorescent in situ hybridization, and the synthesis of artificial genes. Oligonucleotides are also indispensable elements in antisense gene therapy.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of oligonucleotide in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of oligonucleotide in Pythagorean Numerology is: 4
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"oligonucleotide." Definitions.net. STANDS4 LLC, 2024. Web. 19 Mar. 2024. <https://www.definitions.net/definition/oligonucleotide>.
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