What does nociceptin mean?
Definitions for nociceptin
no·ci·ceptin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word nociceptin.
Wiktionary
nociceptinnoun
An neuralogically-active oligopeptide related to the opioids
Wikidata
Nociceptin
Nociceptin or orphanin FQ, a 17 amino acid neuropeptide, is the endogenous ligand for the nociceptin receptor. It is derived from the prepronociceptin protein, as are a further 2 peptides, nocistatin & NocII. The gene coding for prepronociceptin is located on Ch8p21 in humans. Nociceptin is an opioid-related peptide, but it does not act at the classic opioid receptors and its actions are not antagonized by the opioid antagonist naloxone. Nociceptin is a potent anti-analgesic. Nociceptin is widely distributed in the CNS; it is found in many regions of the hypothalamus, brainstem, and forebrain, as well as in the ventral horn and dorsal horn of the spinal cord. Nociceptin acts at the Nociceptin receptor, formerly known as ORL-1. The receptor is also widely distributed in the brain, including in the cortex, anterior olfactory nucleus, lateral septum, hypothalamus, hippocampus, amygdala, central gray, pontine nuclei, interpeduncular nucleus, substantia nigra, raphe complex, locus coeruleus, and spinal cord. The N/OFQ-NOP system is found in central and peripheral nervous tissue, where it is well placed to modulate nociception. Indeed, there is some evidence that nociceptin may be involved in the phenomenon of opioid-induced hyperalgesia.
Anagrams for nociceptin »
concipient
Numerology
Chaldean Numerology
The numerical value of nociceptin in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of nociceptin in Pythagorean Numerology is: 9
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Translations for nociceptin
From our Multilingual Translation Dictionary
- nociceptinArabic
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"nociceptin." Definitions.net. STANDS4 LLC, 2024. Web. 24 Apr. 2024. <https://www.definitions.net/definition/nociceptin>.
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