Definitions for no-observed-adverse-effect level
This page provides all possible meanings and translations of the word no-observed-adverse-effect level
U.S. National Library of Medicine
The highest dosage administered that does not produce toxic effects. The NOAEL will depend on how closely dosages are spaced (lowest-observed-adverse-effect level and no-observed-effect level) and the number of animals examined. The ultimate objective is usually to determine not the "safe" dosage in laboratory animals but the "safe" dosage for humans. Therefore, the extrapolation most often required of toxicologists is from high-dosage studies in laboratory animals to low doses in humans. (Casarett and Doull's Toxicology: The Basic Science of Poisons, 4th ed)
Find a translation for the no-observed-adverse-effect level definition in other languages:
Select another language:
Discuss these no-observed-adverse-effect level definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"no-observed-adverse-effect level." Definitions.net. STANDS4 LLC, 2015. Web. 24 May 2015. <http://www.definitions.net/definition/no-observed-adverse-effect level>.