What does nimotuzumab mean?
Definitions for nimotuzumab
ni·mo·tuzum·ab
This dictionary definitions page includes all the possible meanings, example usage and translations of the word nimotuzumab.
Wiktionary
nimotuzumabnoun
A monoclonal antibody used to treat squamous cell carcinoma, head and neck cancer, nasopharyngeal cancer, and glioma.
Wikipedia
Nimotuzumab
Nimotuzumab (h-R3, BIOMAb EGFR, Biocon, India; TheraCIM, CIMYM Biosciences, Canada; Theraloc, Oncoscience, Europe, CIMAher, Center of Molecular Immunology, Havana, Cuba) is a humanized monoclonal antibody that as of 2014 had orphan status in the US and EU for glioma, and marketing approval in India, China, and other countries for squamous cell carcinomas of the head and neck, and was undergoing several clinical trials. Like cetuximab, nimotuzumab binds to the epidermal growth factor receptor (EGFR), a signalling protein that normally controls cell division. In some cancers, this receptor is altered to cause uncontrolled cell division, a hallmark of cancer. These monoclonal antibodies block EGFR and stop the uncontrolled cell division. It has a humanized human-mouse h-R3 heavy chain and a humanized human-mouse h-R3 κ-chain.
Wikidata
Nimotuzumab
Nimotuzumab is a humanized monoclonal antibody used to treat squamous cell carcinomas of the head and neck, recurrent or refractory high grade malignant glioma, anaplastic astrocytomas, glioblastomas and diffuse intrinsic pontine glioma. Like cetuximab, nimotuzumab binds to the epidermal growth factor receptor, a signalling protein that normally controls cell division. In some cancers, this receptor is altered to cause uncontrolled cell division, a hallmark of cancer. These monoclonal antibodies block EGFR and stop the uncontrolled cell division. Most monoclonal antibodies are originally created by mouse cells, but this can cause an immune reaction to mouse proteins. Humanised antibodies are made using parts of mouse proteins and parts of human proteins, which causes less of an immune reaction. Nimotuzumab contains 95% human antibody sequences. This reduces adverse effects such as rash, diarrhea and conjunctivitis.
Numerology
Chaldean Numerology
The numerical value of nimotuzumab in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of nimotuzumab in Pythagorean Numerology is: 2
Translations for nimotuzumab
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"nimotuzumab." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/nimotuzumab>.
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