Definitions for nfatc transcription factors
This page provides all possible meanings and translations of the word nfatc transcription factors
U.S. National Library of Medicine
NFATC Transcription Factors
A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
Find a translation for the nfatc transcription factors definition in other languages:
Select another language:
Discuss these nfatc transcription factors definitions with the community:
Use the citation below to add this definition to your bibliography:
"nfatc transcription factors." Definitions.net. STANDS4 LLC, 2014. Web. 30 Sep. 2014. <http://www.definitions.net/definition/nfatc transcription factors>.