Neurogenic inflammation is inflammation arising from the local release from afferent neurons of inflammatory mediators such as Substance P and Calcitonin Gene-Related Peptide. This process appears to play an important role in the pathogenesis of numerous diseases including psoriasis, asthma, fibromyalgia, eczema, rosacea, dystonia, multiple chemical sensitivity, and migraine. In migraine, stimulation of the trigeminal nerve causes neurogenic inflammation via release of neuropeptides including Substance P, nitric oxide, vasoactive intestinal polypeptide, 5-HT, Neurokinin A and CGRP. leading to a "sterile neurogenic inflammation."
U.S. National Library of Medicine
Inflammation caused by an injurious stimulus of peripheral neurons and resulting in release of neuropeptides which affect vascular permeability and help initiate proinflammatory and immune reactions at the site of injury.
The numerical value of neurogenic inflammation in Chaldean Numerology is: 5
The numerical value of neurogenic inflammation in Pythagorean Numerology is: 4
Images & Illustrations of neurogenic inflammation
Find a translation for the neurogenic inflammation definition in other languages:
Select another language:
Discuss these neurogenic inflammation definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"neurogenic inflammation." Definitions.net. STANDS4 LLC, 2017. Web. 30 May 2017. <http://www.definitions.net/definition/neurogenic inflammation>.