Definitions for neurofilament
neu·ro·fil·a·ment

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1. neurofilamentnoun

   A neurofibril

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1. Neurofilament

   Neurofilaments (NF) are classed as type IV intermediate filaments found in the cytoplasm of neurons. They are protein polymers measuring 10 nm in diameter and many micrometers in length. Together with microtubules (~25 nm) and microfilaments (7 nm), they form the neuronal cytoskeleton. They are believed to function primarily to provide structural support for axons and to regulate axon diameter, which influences nerve conduction velocity. The proteins that form neurofilaments are members of the intermediate filament protein family, which is divided into six types based on their gene organization and protein structure. Types I and II are the keratins which are expressed in epithelia. Type III contains the proteins vimentin, desmin, peripherin and glial fibrillary acidic protein (GFAP). Type IV consists of the neurofilament proteins L, M, H and internexin. Type V consists of the nuclear lamins, and type VI consists of the protein nestin. The type IV intermediate filament genes all share two unique introns not found in other intermediate filament gene sequences, suggesting a common evolutionary origin from one primitive type IV gene. Any proteinaceous filament that extends in the cytoplasm of a nerve cell is also termed a neurofibril. This name is used in the neurofibrillary tangles of some neurodegenerative diseases.

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1. Neurofilament

   Neurofilaments are the 10 nanometer or intermediate filaments found in neurons. They are a major component of the neuronal cytoskeleton, and are believed to function primarily to provide structural support for the axon and to regulate axon diameter. Neurofilaments are composed of polypeptide chains or subunits which belong to the same protein family as the intermediate filaments of other tissues such as keratin subunits, which make 10 nm filaments expressed specifically in epithelia. The family of proteins making intermediate filaments is divided into 5 major classes, the keratins forming the classes I and II. Class III contains the proteins vimentin, desmin, peripherin and glial fibrillary acidic protein. The major neurofilament subunits occupy the class IV family of intermediate filaments, along with two other filament proteins of neurons, alpha-internexin and nestin. The class IV intermediate filament genes all share two unique introns not found in other intermediate filament gene sequences, suggesting a common evolutionary origin from one primitive class IV gene. Finally, class V corresponds to intermediate filaments of the nuclear cytoskeleton, the nuclear lamins.

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Numerology

1. Chaldean Numerology

   The numerical value of neurofilament in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of neurofilament in Pythagorean Numerology is: 9

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Neurofilament
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Neurofilament
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=neurofilament