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1. (n.) neurofibroma
a benign neoplasm composed of the fibrous elements of a nerve.
Etymology: (1890–95)
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| Definition of 'neurofibroma' |
Princeton's WordNet |
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1. (noun) neurofibroma, neurilemoma
tumor of the fibrous covering of a peripheral nerve
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| Definition of 'neurofibroma' |
U.S. National Library of Medicine |
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1. neurofibroma
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
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