This page provides all possible meanings and translations of the word nafoxidine
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A triphenylethylene nonsteroidal agent that acts as a partial estrogen antagonist. Nafoxidine competes with endogenous estrogen for binding to specific estrogen receptors. This agent also inhibits angiogenesis in some tissues by blocking the effects of fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF); paradoxically, it may enhance angiogenesis in uterine tissue. Nafoxidine also induces oxidative stress, protein kinase C and calcium signaling. (NCI04)
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An estrogen antagonist that has been used in the treatment of breast cancer.
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