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1. (n.) multiple sclerosis
a chronic degenerative disease marked by patchy destruction of the myelin that surrounds and insulates nerve fibers and mild to severe neural and muscular impairments.
Etymology: (1880–85)
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| Definition of 'multiple sclerosis' |
Princeton's WordNet |
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1. (noun) multiple sclerosis, MS, disseminated sclerosis, disseminated multiple sclerosis
a chronic progressive nervous disorder involving loss of myelin sheath around certain nerve fibers
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| Definition of 'multiple sclerosis' |
U.S. National Library of Medicine |
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1. multiple sclerosis
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
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