Definitions for mucociliary clearance
This page provides all possible meanings and translations of the word mucociliary clearance
Mucociliary clearance, also referred to as mucociliary apparatus or mucociliar clearance, derived from mucus, cilia and clearance describes the self-clearing mechanism of the bronchi. The passage of airway in the respiratory tract that conducts air into the lungs main bronchi down to the final branchings of the respiratory tree alveoli are lined with a moist lining of the airway respiratory epithelium. On that, cilium is present, bearing hair-shaped structures on its surface. The cilia are surrounded by a thin fluid film of mucus. On top of that is a second viscous film of mucus, in which foreign particles and microorganisms get stuck. Within the thin fluid film of mucus the cilia act out movements coordinated in direction towards the pharynx. Thereby the viscous film of mucus including its freight is transported off in direction towards the mouth, where it is either swallowed or expelled via coughing. Important for good mucociliary clearance are the number of cilia, their structure, activity, and coordinated movement. Optimum functionality of mucociliary clearance presuppose a temperature of 37 °C and an absolute humidity of 44 mg/dm³ corresponding to a relative humidity of 100%. Under the condition of insufficient temperature and humidity, after a short time the ciliary cells suspend their transport function. Under such circumstances, bacterial germinal colonization is facilitated. Pulmonary infections and damaging of the pulmonic tissues may be the consequence.
U.S. National Library of Medicine
A non-specific host defense mechanism that removes MUCUS and other material from the LUNGS by ciliary and secretory activity of the tracheobronchial submucosal glands. It is measured in vivo as mucus transfer, ciliary beat frequency, and clearance of radioactive tracers.
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