Definitions for mucociliary clearance
mu·cocil·ia·ry clear·ance

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1. Mucociliary clearance

   Mucociliary clearance (MCC), mucociliary transport, or the mucociliary escalator, describes the self-clearing mechanism of the airways in the respiratory system. It is one of the two protective processes for the lungs in removing inhaled particles including pathogens before they can reach the delicate tissue of the lungs. The other clearance mechanism is provided by the cough reflex. Mucociliary clearance has a major role in pulmonary hygiene. MCC effectiveness relies on the correct properties of the airway surface liquid produced, both of the periciliary sol layer and the overlying mucus gel layer, and of the number and quality of the cilia present in the lining of the airways. An important factor is the rate of mucin secretion. The ion channels CFTR and ENaC work together to maintain the necessary hydration of the airway surface liquid.Any disturbance in the closely regulated functioning of the cilia can cause a disease. Disturbances in the structural formation of the cilia can cause a number of ciliopathies, notably primary ciliary dyskinesia. Cigarette smoke exposure can cause shortening of the cilia.

WikidataRate this definition:0.0 / 0 votes

1. Mucociliary clearance

   Mucociliary clearance, also referred to as mucociliary apparatus or mucociliar clearance, derived from mucus, cilia and clearance describes the self-clearing mechanism of the bronchi. The passage of airway in the respiratory tract that conducts air into the lungs main bronchi down to the final branchings of the respiratory tree alveoli are lined with a moist lining of the airway respiratory epithelium. On that, cilium is present, bearing hair-shaped structures on its surface. The cilia are surrounded by a thin fluid film of mucus. On top of that is a second viscous film of mucus, in which foreign particles and microorganisms get stuck. Within the thin fluid film of mucus the cilia act out movements coordinated in direction towards the pharynx. Thereby the viscous film of mucus including its freight is transported off in direction towards the mouth, where it is either swallowed or expelled via coughing. Important for good mucociliary clearance are the number of cilia, their structure, activity, and coordinated movement. Optimum functionality of mucociliary clearance presuppose a temperature of 37 °C and an absolute humidity of 44 mg/dm³ corresponding to a relative humidity of 100%. Under the condition of insufficient temperature and humidity, after a short time the ciliary cells suspend their transport function. Under such circumstances, bacterial germinal colonization is facilitated. Pulmonary infections and damaging of the pulmonic tissues may be the consequence.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Mucociliary Clearance

   A non-specific host defense mechanism that removes MUCUS and other material from the LUNGS by ciliary and secretory activity of the tracheobronchial submucosal glands. It is measured in vivo as mucus transfer, ciliary beat frequency, and clearance of radioactive tracers.

How to pronounce mucociliary clearance?

1. Alex

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Numerology

1. Chaldean Numerology

   The numerical value of mucociliary clearance in Chaldean Numerology is: 6

2. Pythagorean Numerology

   The numerical value of mucociliary clearance in Pythagorean Numerology is: 2

References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/Mucociliary_Clearance
2. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=mucociliary clearance