Definitions for mice, knockout

This page provides all possible meanings and translations of the word mice, knockout

U.S. National Library of Medicine

  1. Mice, Knockout

    Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.

Translation

Find a translation for the mice, knockout definition in other languages:

Select another language:

Discuss these mice, knockout definitions with the community:


Citation

Use the citation below to add this definition to your bibliography:

Style:MLAChicagoAPA

"mice, knockout." Definitions.net. STANDS4 LLC, 2014. Web. 18 Dec. 2014. <http://www.definitions.net/definition/mice, knockout>.

Are we missing a good definition for mice, knockout?


The Web's Largest Resource for

Definitions & Translations


A Member Of The STANDS4 Network


Nearby & related entries:

Alternative searches for mice, knockout: