Definitions for methadone
ˈmɛθ əˌdoʊn; -ˌdɒnmethadone

Princeton's WordNetRate this definition:0.0 / 0 votes

1. methadone, methadone hydrochloride, methadon, dolophine hydrochloride, fixer, synthetic heroinnoun

   synthetic narcotic drug similar to morphine but less habit-forming; used in narcotic detoxification and maintenance of heroin addiction

WiktionaryRate this definition:0.0 / 0 votes

1. methadonenoun

   A synthetic opioid analgesic, used to wean addicts off of heroin or other opiate based narcotics, and in chronic pain management.

WikipediaRate this definition:0.0 / 0 votes

1. Methadone

   Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid dependence. It is used to treat chronic pain, and it is also used to treat addiction to heroin or other opioids. Prescribed for daily use, the medicine relieves cravings and removes withdrawal symptoms. Detoxification using methadone can be accomplished in less than a month, or it may be done gradually over as long as for the rest of the patient’s life. While a single dose has a rapid effect, maximum effect can take up to five days of use. The pain-relieving effects last about six hours after a single dose. After long-term use, in people with normal liver function, effects last 8 to 36 hours. Methadone is usually taken by mouth and rarely by injection into a muscle or vein.Side effects are similar to those of other opioids. These frequently include dizziness, sleepiness, vomiting, and sweating. Serious risks include opioid abuse and respiratory depression. Abnormal heart rhythms may also occur due to a prolonged QT interval. The number of deaths in the United States involving methadone poisoning declined from 4,418 in 2011 to 3,300 in 2015. Risks are greater with higher doses. Methadone is made by chemical synthesis and acts on opioid receptors.Methadone was developed in Germany around 1937 to 1939 by Gustav Ehrhart and Max Bockmühl. It was approved for use as an analgesic in the United States in 1947, and has been used in the treatment of addiction since the 1960s. It is on the World Health Organization's List of Essential Medicines.

ChatGPTRate this definition:0.0 / 0 votes

1. methadone

   Methadone is a synthetic opioid medication commonly used to treat opioid addiction and dependence, such as heroin addiction. It works by reducing the withdrawal symptoms and reducing cravings for the addictive drug. In some cases, it is also employed to manage chronic pain conditions. Methadone is generally used as part of a comprehensive treatment program that includes counseling and participation in social support programs. It should be administered under the supervision of a healthcare provider, due to its potentially addictive nature.

WikidataRate this definition:0.0 / 0 votes

1. Methadone

   Methadone is a synthetic opioid. It is used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependency. It was developed in Germany in 1937, mainly because Germany required a reliable internal source of opiates. Because it is an acyclic analog of morphine or heroin, methadone acts on the same opioid receptors as these drugs, and thus has many of the same effects. Methadone is also used in managing severe chronic pain, owing to its long duration of action, extremely powerful effects, and very low cost. Methadone was introduced into the United States in 1947 by Eli Lilly and Company. Methadone results in about 5,000 deaths per year. Methadone is mainly used in the treatment of opioid dependence. It has cross-tolerance with other opioids including heroin and morphine, offering very similar effects and a longer duration of effect. Oral doses of methadone can stabilise patients by mitigating opioid withdrawal syndrome. Higher doses of methadone can block the euphoric effects of heroin, morphine, and similar drugs. As a result, properly dosed methadone patients can reduce or stop altogether their use of these substances.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Methadone

   A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. It also has a depressant action on the cough center and may be given to control intractable cough associated with terminal lung cancer. Methadone is also used as part of the treatment of dependence on opioid drugs, although prolonged use of methadone itself may result in dependence. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)

Matched Categories

1. • Narcotic

How to pronounce methadone?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say methadone in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of methadone in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of methadone in Pythagorean Numerology is: 4

Examples of methadone in a Sentence

1. Jim Bianco:

   The era of easy money would officially be over, a rate hike would mean putting the needle away, no more drugs, time for the methadone.

2. Joe Alioto:

   We should befeeding their stomachs, nottheir addictions, i guess they feel as though the rest of us can fend for ourselves, I thinkthe real concern here by the Department of Health is, to givethem a little bit of credit,they dont want to spread theCOVID disease... [But] some of these homeless people who are being housed in the hotels specific to this program --that are getting methadone,marijuana, alcohol, some of themare not even COVID positive, butwhat they are trying to do isforce them into self-isolationby feeding these addictions.

3. Caleb Banta-Green:

   It’s a conversation starter. It’s life-saving for the individual. It’s not a game-changer at the population level, we need to do more. And we need to use treatment medications – methadone and buprenorphine – which are far higher overdose preventive approaches.

4. Dan Werb:

   We have decades of evidence suggesting that methadone and similar opioid-based medications can be really effective in helping people to manage their opioid use.

5. Caleb Banta-Green:

   The good news is that among all drugs of abuse, heroin and opioids have by far the best treatment medications available. Methadone and buprenorphine have proven effectiveness data, they not only reduce the chances of dying from an opioid overdose by 50%, they support people being in recovery from their addiction and reduce health care costs and improve a wide array of other outcomes.

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=methadone
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Methadone
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Methadone
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=methadone