Definitions of mannose-binding protein-associated serine proteases

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Definition of 'mannose-binding protein-associated serine proteases'

U.S. National Library of Medicine

1. mannose-binding protein-associated serine proteases
Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.

'mannose-binding protein-associated serine proteases' - Nearby Entries
mannose-6-phosphate isomerase mannose-binding lectin mannose-binding lectins mannose-binding protein-associated serine proteases mannosephosphates mannosidase deficiency diseases mannosidases

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