Definitions for macrophage colony-stimulating factor
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Macrophage colony-stimulating factor
Macrophage colony-stimulating factor, or M-CSF, is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. M-CSF binds to the Colony stimulating factor 1 receptor. It may also be involved in development of the placenta.
U.S. National Library of Medicine
Macrophage Colony-Stimulating Factor
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
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"macrophage colony-stimulating factor." Definitions.net. STANDS4 LLC, 2015. Web. 25 Nov. 2015. <http://www.definitions.net/definition/macrophage colony-stimulating factor>.