What does lysostaphin mean?

Definitions for lysostaphin

Here are all the possible meanings and translations of the word lysostaphin.

Wiktionary

  1. lysostaphin(Noun)

    An antibiotic obtained from Staphylococcus simulans

Freebase

  1. Lysostaphin

    Lysostaphin is a Staphylococcus simulans metalloendopeptidase. It can function as an antimicrobial against Staphylococcus aureus. Lysostaphin is a 27 KDa glycylglycine endopeptidase, an antibacterial enzyme which is capable of cleaving the crosslinking pentaglycin bridges in the cell wall of Staphylococci. Lysostaphin was first isolated from a culture of Staphylococcus simulans by Schindler and Schuhardt in 1964. S. aureus cell walls contain high proportions of pentaglycin, making lysostaphin a highly effective agent against both actively growing and quiescent bacteria. Staphylococcal infections of both Staphylococcus aureus and Staphylococcus epidermidis continue to be a major issue in clinical settings, particularly those with implantable devices. Staphylococci cause a significant percentage of device infections, and like many other pathogens, rather than living as free planktonic cells within the host they have the ability to form a multilayered community of sessile bacteria cells known as a biofilm on implantable devices. Once a "Staphylococcal" biofilm has formed on an implanted medical device, it is difficult to disrupt due to its antibiotic resistance and protection against bacterial action.

U.S. National Library of Medicine

  1. Lysostaphin

    A 25-kDa peptidase produced by Staphylococcus simulans which cleaves a glycine-glcyine bond unique to an inter-peptide cross-bridge of the STAPHYLOCOCCUS AUREUS cell wall. EC 3.4.24.75.

Numerology

  1. Chaldean Numerology

    The numerical value of lysostaphin in Chaldean Numerology is: 5

  2. Pythagorean Numerology

    The numerical value of lysostaphin in Pythagorean Numerology is: 5

Images & Illustrations of lysostaphin

  1. lysostaphin

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