Definitions of lovastatin [ˌloʊ vəˈstæt n]

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Definition of 'lovastatin'

Random House Webster's College Dictionary

1. (n.) lovastatin
a drug that reduces the levels of fats in the blood by altering the enzyme activity in the liver that produces lipids.

Etymology: (1985–90; of undetermined orig.)

Definition of 'lovastatin'

Princeton's WordNet

1. (noun) lovastatin, Mevacor
an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate

Definition of 'lovastatin'

U.S. National Library of Medicine

1. lovastatin
A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.

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