Definitions for lovastatinˌloʊ vəˈstæt n
This page provides all possible meanings and translations of the word lovastatin
Random House Webster's College Dictionary
lo•va•stat•inˌloʊ vəˈstæt n(n.)
a drug that reduces the levels of fats in the blood by altering the enzyme activity in the liver that produces lipids.
Origin of lovastatin:
1985–90; of undetermined orig.
an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate
A statin that inhibits the synthesis of cholesterol
Lovastatin is a member of the drug class of statins, used in combination with diet, weight-loss, and exercise for lowering cholesterol in those with hypercholesterolemia to reduce risk of cardiovascular disease. Lovastatin is a naturally occurring drug found in food such as oyster mushrooms and red yeast rice.
U.S. National Library of Medicine
A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
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