What does lissencephaly mean?

Definitions for lissencephaly
lissencepha·ly

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Wiktionary

  1. lissencephalynoun

    A disorder characterized by smoothness (lack of folds and grooves) of the brain.

Wikipedia

  1. Lissencephaly

    Lissencephaly (, meaning 'smooth brain') is a set of rare brain disorders whereby the whole or parts of the surface of the brain appear smooth. It is caused by defective neuronal migration during the 12th to 24th weeks of gestation resulting in a lack of development of brain folds (gyri) and grooves (sulci). It is a form of cephalic disorder. Terms such as agyria (no gyri) and pachygyria (broad gyri) are used to describe the appearance of the surface of the brain. Children with lissencephaly generally have significant developmental delays, but these vary greatly from child to child depending on the degree of brain malformation and seizure control. Life expectancy can be shortened, generally due to respiratory problems.

Wikidata

  1. Lissencephaly

    Lissencephaly, which literally means smooth brain, is a rare brain formation disorder caused by defective neuronal migration during the 12th to 24th weeks of gestation resulting in a lack of development of brain folds and grooves. It is a form of cephalic disorder. Terms such as 'agyria' or 'pachygyria' are used to describe the appearance of the surface of the brain. Children with Lissencephaly generally have significant developmental delays, but these vary greatly from child to child depending on the degree of brain malformation, and seizure control. Life expectancy can be shortened, generally due to respiratory problems.

U.S. National Library of Medicine

  1. Lissencephaly

    A "smooth brain" malformation of the CEREBRAL CORTEX resulting from abnormal location of developing neurons during corticogenesis. It is characterized by an absence of normal convoluted indentations on the surface of the brain (agyria), or fewer and shallower indentations (pachygryia). There is a reduced number of cortical layers, typically 4 instead of 6, resulting in a thickened cortex, and reduced cerebral white matter that is a reversal of the normal ratio of cerebral white matter to cortex.

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Numerology

  1. Chaldean Numerology

    The numerical value of lissencephaly in Chaldean Numerology is: 1

  2. Pythagorean Numerology

    The numerical value of lissencephaly in Pythagorean Numerology is: 4

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"lissencephaly." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/lissencephaly>.

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