Definitions for lamivudine
This page provides all possible meanings and translations of the word lamivudine
a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIV
A nucleoside analog reverse transcriptase inhibitor, 2',3'-dideoxy-3'-thiacytidine that is used for the treatment of HIV and chronic hepatitis B
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor. It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus mutant. Despite this, lamivudine is still used widely as it is well tolerated.
U.S. National Library of Medicine
A reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
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