What does kynurenine mean?

Definitions for kynurenine
kynure·nine

This dictionary definitions page includes all the possible meanings, example usage and translations of the word kynurenine.

Wiktionary

  1. kynureninenoun

    A metabolite, 2-amino-4-(2-aminophenyl)- 4-oxo-butanoic acid, that is an intermediate in the conversion of tryptophan to niacin

Wikidata

  1. Kynurenine

    L-Kynurenine is a metabolite of the amino acid L-tryptophan used in the production of niacin. Kynurenine is synthesized by the enzyme tryptophan dioxygenase, which is made primarily but not exclusively in the liver, and indoleamine 2,3-dioxygenase which is made in many tissues in response to immune activation. Kynurenine and its further breakdown products carry out diverse biological functions, including dilating blood vessels during inflammation and regulating the immune response. Some cancers increase kynurenine production, which increases tumor growth. Evidence suggests that increased kynurenine production may precipitate depressive symptoms associated with interferon treatment for hepatitis C. Cognitive deficits in schizophrenia are associated with imbalances in the enzymes that break down kynurenine. Kynurenine production is increased in Alzheimer's disease and cardiovascular disease where its metabolites are associated with cognitive deficits and depressive symptoms. Kynurenine is also associated with tics. Kynureninase catabolizes the conversion of kynurenine into anthranilic acid while kynurenine-oxoglutarate transaminase catabolizes its conversion into kynurenic acid. Kynurenine 3-hydroxylase converts kynurenine to 3-hydroxykynurenine.

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Numerology

  1. Chaldean Numerology

    The numerical value of kynurenine in Chaldean Numerology is: 1

  2. Pythagorean Numerology

    The numerical value of kynurenine in Pythagorean Numerology is: 1

Examples of kynurenine in a Sentence

  1. David Gruber:

    The exciting part of this study is the description of an entirely new form of marine biofluorescence from sharks -- one that is based on brominated tryptophan-kynurenine small-molecule metabolites.

Popularity rank by frequency of use

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"kynurenine." Definitions.net. STANDS4 LLC, 2024. Web. 16 Apr. 2024. <https://www.definitions.net/definition/kynurenine>.

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