What does kininogen, high-molecular-weight mean?
Definitions for kininogen, high-molecular-weight
kininogen, high-molec·ular-weight
This dictionary definitions page includes all the possible meanings, example usage and translations of the word kininogen, high-molecular-weight.
Wikipedia
kininogen, high-molecular-weight
High-molecular-weight kininogen (HMWK or HK) is a circulating plasma protein which participates in the initiation of blood coagulation, and in the generation of the vasodilator bradykinin via the kallikrein-kinin system. HMWK is inactive until it either adheres to binding proteins beneath an endothelium disrupted by injury, thereby initiating coagulation; or it binds to intact endothelial cells or platelets for functions other than coagulation.
U.S. National Library of Medicine
Kininogen, High-Molecular-Weight
A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)
Numerology
Chaldean Numerology
The numerical value of kininogen, high-molecular-weight in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of kininogen, high-molecular-weight in Pythagorean Numerology is: 5
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