Definitions for ketorolac tromethamine
This page provides all possible meanings and translations of the word ketorolac tromethamine
ketorolac tromethamine, Acular, Toradol(noun)
nonsteroidal anti-inflammatory drug (trade names Acular and Toradol) that is administered only intramuscularly
U.S. National Library of Medicine
A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is a non-steroidal anti-inflammatory agent used for analgesia for postoperative pain and inhibits cyclooxygenase activity.
Ketorolac or ketorolac tromethamine is a non-steroidal anti-inflammatory drug in the family of heterocyclic acetic acid derivatives, used as an analgesic. Ketorolac was developed in 1989 by Syntex Corp.. It was approved by FDA on 30 November 1989 and introduced as Toradol by Syntex. The ophthalmic form was approved by FDA on 9 November 1992 and was introduced as Acular eye drops by Allergan under license from Syntex. An intranasal formulation of ketorolac tromethamine was approved by FDA on 14 May 2010 and introduced as Sprix Nasal Spray by Daiichi Sankyo for short-term management of moderate to moderately severe pain requiring analgesia at the opioid level. In India it is available as Ketanov by Ranbaxy, which is owned by Daiichi Sankyo. Ketorolac acts by inhibiting the bodily synthesis of prostaglandins. Ketorolac in its oral and intramuscular preparations is a racemic mixture of both--ketorolac, the active isomer, and--ketorolac. An ophthalmic solution of ketorolac is available and is used to treat eye pain and to relieve the itchiness and burning of seasonal allergies.
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