Definitions for keratohyalin
This page provides all possible meanings and translations of the word keratohyalin
A protein structure found in granules in the stratum granulosum of the epidermis, which may be involved in keratinization, and in Hassall corpuscles in the thymus.
Keratohyalin is a protein structure found in granules in the stratum granulosum of the epidermis, which may be involved in keratinization, and in Hassall corpuscles in the thymus. In H&E stained sections, they are large deeply stained granules found in the cytoplasm of epithelial cells in keratinized oral mucosa. Keratohyalin is associated with eleidin, the intermediate between keratohyalin and keratin; histological location is in the stratum lucidum, thick skin. In the stratum granulosum, the "grainy" third layer of the human epidermis, the protein Keratohyalin forms dense cytoplasmic granules that promote dehydration of the cell as well as aggregation and cross-linking of the keratin fibers. The nuclei and other organelles then disintegrate, and the cells die. Further dehydration creates a tightly interlocked layer of cells that consists of keratin fibers surrounded by keratohyalin.
Find a translation for the keratohyalin definition in other languages:
Select another language:
Use the citation below to add this definition to your bibliography:
"keratohyalin." Definitions.net. STANDS4 LLC, 2013. Web. 5 Dec. 2013. <http://www.definitions.net/definition/keratohyalin>.