1. (verb)keep up maintain a required pace or level "He could not keep up and dropped out of the race"
2. (verb)prolong, sustain, keep up lengthen or extend in duration or space "We sustained the diplomatic negotiations as long as possible"; "prolong the treatment of the patient"; "keep up the good work"
3. (verb)conserve, preserve, maintain, keep up keep in safety and protect from harm, decay, loss, or destruction "We preserve these archeological findings"; "The old lady could not keep up the building"; "children must be taught to conserve our national heritage"; "The museum curator conserved the ancient manuscripts"
4. (verb)keep up, keep abreast, follow keep informed
"He kept up on his country's foreign policies"
5. (verb)keep up prevent from going to bed at night "The anticipation of the trip kept the children up all night"; "I kept myself up all night studying for the exam"