Definitions for kearns-sayre syndrome

This page provides all possible meanings and translations of the word kearns-sayre syndrome

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  1. Kearns-Sayre syndrome(Noun)

    Oculocraniosomatic disease.

U.S. National Library of MedicineRate this definition:(0.00 / 0 votes)

  1. Kearns-Sayre Syndrome

    A mitochondrial disorder featuring the triad of chronic progressive EXTERNAL OPHTHALMOPLEGIA, cardiomyopathy (CARDIOMYOPATHIES) with conduction block (HEART BLOCK), and RETINITIS PIGMENTOSA. Disease onset is in the first or second decade. Elevated CSF protein, sensorineural deafness, seizures, and pyramidal signs may also be present. Ragged-red fibers are found on muscle biopsy. (Adams et al., Principles of Neurology, 6th ed, p984)


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