disintegration and dissolution of a cell nucleus when a cell dies
The dissolution of the nucleus of a cell by the action of deoxyribonuclease
Karyolysis is the complete dissolution of the chromatin matter of a dying cell due to the activity of DNase. The whole cell will eventually stain uniformly with eosin after karyolysis. It is usually preceded by karyorrhexis and occurs mainly as a result of necrosis, while in apoptosis after karyorrhexis the nucleus usually dissolves into apoptotic bodies.
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