Definitions for kaposi's sarcomaˈkɑ pə siz, ˈkæp ə-
This page provides all possible meanings and translations of the word kaposi's sarcoma
Random House Webster's College Dictionary
Ka′po•si's sarco′maˈkɑ pə siz, ˈkæp ə-(n.)
a cancer of connective tissue characterized by painless purplish red blotches appearing on the skin.
Origin of Kaposi's sarcoma:
after Hungarian dermatologist Moritz Kaposi, or Moriz Kohn (1837–1902), who described it in 1872
a sarcoma that starts with purplish spots on the feet and legs and spreads from the skin to lymph nodes and internal organs; a common manifestation of AIDS
"until 1980 Kaposi's sarcoma occurred almost exclusively with Jewish or Italian or black men"
Kaposi sarcoma is a tumor caused by Human herpesvirus 8, also known as Kaposi sarcoma-associated herpesvirus. It was originally described by Moritz Kaposi, a Hungarian dermatologist practicing at the University of Vienna in 1872. It became more widely known as one of the AIDS-defining illnesses in the 1980s. The viral cause for this cancer was discovered in 1994. Although KS is now well-established to be caused by a viral infection, there is widespread lack of awareness of this even among persons at risk for KSHV/HHV-8 infection. Kaposi’s sarcoma is a systemic disease that can present with cutaneous lesions with or without internal involvement. Four subtypes have been described: Classic KS, affecting middle aged men of Mediterranean descent; African endemic KS; KS in iatrogenically immunosuppressed patients; and AIDS-related KS. The erythematous to violaceous cutaneous lesions seen in KS have several morphologies: macular, patch, plaque, nodular, and exophytic. The cutaneous lesions can be solitary, localized or disseminated. KS can involve the oral cavity, lymph nodes, and viscera. Classic KS tends to be indolent, presenting with erythematous or violaceous patches on the lower extremities. African endemic KS and AIDS-related KS tend to be more aggressive. The AIDS-related KS lesions often rapidly progress to plaques and nodules affecting the upper trunk, face, and oral mucosa. The diagnosis can be made with a tissue biopsy and, if clinically indicated, internal imaging should be done.
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