Definitions for junin virus
This page provides all possible meanings and translations of the word junin virus
the RNA virus that causes Argentine hemorrhagic fever; carried by rats and mice
The Junin Virus virion is a negative sense ssRNA enveloped with a variable diameter of between 50 and 300 nm. The surface of the particle encompasses a layer of T-shaped glycoprotein extensions, extending up to 10 nm from the envelope, which are important for mediating attachment and entry into host cells. The Junin virus genome comprises two single stranded RNA molecules, each encoding two different genes in an ambisense orientation. The two segments are termed 'short' and 'long' due to their respective lengths. The short segment encodes the nucleocapsid protein and the glycoprotein precursor. The GPC is subsequently cleaved to form two viral glycoproteins, GP1 and GP2 which ultimately form the T-shaped glycoprotein spike which extends from the viral envelope. The long segment encodes the viral polymerase and a zinc binding protein. It is spread by rodents
U.S. National Library of Medicine
A species of ARENAVIRUS, part of the New World Arenaviruses (ARENAVIRUSES, NEW WORLD), causing Argentinian hemorrhagic fever. The disease is characterized by congestion, edema, generalized lymphadenopathy and hemorrhagic necrosis and is sometimes fatal.
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